Recombinant Human GH Instruction

General description

Growth Hormone is a pituitary peptide that regulates postnatal growth, metabolism, and body composition. It stimulates IGF-1 production and promotes cell proliferation, protein synthesis, and lipolysis. Recombinant Human GH Protein (Y07601) is expressed from mammalian cells. It contains AA Phe 27-Phe 217 (Accession # P01241), and is widely used in advanced cell culture, metabolic research, and cell proliferation studies.

Application

· Cell Proliferation and Protein Synthesis — Promotes anabolic growth in diverse cell types.

· Metabolic Regulation Research — Models GH effects on glucose and lipid metabolism.

· Adipocyte Differentiation and Lipolysis — Regulates fat cell development and triglyceride breakdown.

· Chondrocyte and Growth Plate Biology — Supports cartilage cell proliferation and endochondral ossification.

· Serum-Free Culture Systems — Suitable for chemically defined and xeno-free cell culture media.

Product Specifications

Stability and Reconstitution

· 36 months at -20°C to -80°C in lyophilized state;

· 6 months at -20°C to -80°C under sterile conditions after reconstitution;

· 7-10 days at 2°C to 8°C under sterile conditions after reconstitution;

· Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

· It is recommended to redissolve in sterile deionized water.

Backgroud

GH is a 191-amino acid polypeptide produced by somatotrophs in the anterior pituitary. It signals through the GH receptor, activating JAK2-dependent STAT5, PI3K-AKT, and MAPK pathways. GH stimulates hepatic IGF-1 production, which mediates many of its growth-promoting effects. Clinically, recombinant GH treats growth hormone deficiency, Turner syndrome, and short bowel syndrome. In cell culture, GH supports cell proliferation, metabolic studies, and models of growth regulation.

Q&A

Q1: What is GH mainly used for?

GH is primarily used for cell proliferation, metabolic research, adipocyte biology, and chondrocyte culture.

Q2: Is this GH suitable for serum-free culture systems?

Yes. EastMabBio recombinant GH is compatible with serum-free, xeno-free, and chemically defined media systems.

Q3: How should recombinant GH be stored?

Lyophilized protein should be stored at -20°C or below. After reconstitution, aliquot and avoid repeated freeze-thaw cycles.

Q4: What shipping conditions are used?

Products are shipped on dry ice with validated cold-chain packaging to maintain stability during international transportation.

Q5: Do you provide QC documents?

Yes. COA, MSDS, TSE-BSE statements, endotoxin reports, bioactivity data, and additional QC documentation are available upon request.